Open AccessThe Osteogenic Role of Barium Titanate/Polylactic Acid Piezoelectric Composite Membranes as Guiding Membranes for Bone Tissue Regeneration
Author(s) -
Xianglin Dai,
Xijun Yao,
Wenfeng Zhang,
Hongyuan Cui,
Yifan Ren,
Jiupeng Deng,
Xia Zhang
Publication year - 2022
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s378422
Subject(s) - materials science , membrane , polylactic acid , biocompatibility , in vivo , barium titanate , biomedical engineering , bone tissue , alkaline phosphatase , biophysics , regeneration (biology) , composite material , chemistry , biochemistry , microbiology and biotechnology , ceramic , medicine , biology , enzyme , polymer , metallurgy
Biopiezoelectric materials have good biocompatibility and excellent piezoelectric properties, and they can generate local currents in vivo to restore the physiological electrical microenvironment of the defect and promote bone regeneration. Previous studies of guided bone regeneration membranes have rarely addressed the point of restoring it, so this study prepared a Barium titanate/Polylactic acid (BT/PLA) piezoelectric composite membrane and investigated its bone-formation, with a view to providing an experimental basis for clinical studies of guided bone tissue regeneration membranes.