Open AccessConstruction Of High Loading Natural Active Substances Nanoplatform and Application in Synergistic Tumor Therapy
Author(s) -
Haoqiang Liu,
Zeyidan Jiapaer,
Fanxing Meng,
Wanfeng Wu,
Chengyi Hou,
Mengjiao Duan,
Yueping Qin,
Shuxuan Shao,
Minwei Zhang
Publication year - 2022
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s364108
Subject(s) - nanocarriers , in vivo , photothermal therapy , materials science , nanotechnology , drug delivery , chemistry , microbiology and biotechnology , biology
Natural bioactive substances have been widely studied for their superior anti-tumor activity and low toxicity. However, natural bioactive substances suffer from poor water-solubility and poor stability in the physiological environment. Therefore, to overcome the drawbacks of natural bioactive substances in tumor therapy, there is an urgent need for an ideal nanocarrier to achieve high bioactive substance loading with low toxicity.