Open AccessMercaptopurine-Loaded Sandwiched Tri-Layered Composed of Electrospun Polycaprolactone/Poly(Methyl Methacrylate) Nanofibrous Scaffolds as Anticancer Carrier with Antimicrobial and Antibiotic Features: Sandwich Configuration Nanofibers, Release Study and in vitro Bioevaluation Tests
Author(s) -
Samar A. Salim,
Elbadawy A. Kamoun,
Stephen W Evans,
Shahira H. EL-Moslamy,
Esmail M. ElFakharany,
Mohamed M. Elmazar,
Azza Abdel-Aziz,
RH Abou-Saleh,
Taher A. Salaheldin
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s332920
Subject(s) - polycaprolactone , materials science , nanofiber , poly(methyl methacrylate) , methyl methacrylate , electrospinning , crystallinity , chemical engineering , composite material , polymer , polymerization , engineering
6-Mercaptopurine (6-MP) is a potential anti-cancer agent which its therapeutic and limitation applicability due to its high toxicity.