Open AccessSynergistic Therapy Using Doxorubicin-Loading and Nitric Oxide-Generating Hollow Prussian Blue Nanoparticles with Photoacoustic Imaging Potential Against Breast Cancer
Author(s) -
Jijun Fu,
Qianni Wu,
Yanan Dang,
Xueping Lei,
Gui-ning Feng,
Mingyue Chen,
Xiyong Yu
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s327598
Subject(s) - doxorubicin , nanocarriers , prussian blue , materials science , nitric oxide , nanoparticle , cancer research , biophysics , pharmacology , chemistry , chemotherapy , nanotechnology , medicine , biology , organic chemistry , electrode , electrochemistry
Traditional antitumor chemotherapy faces great challenges, such as multi-drug resistance (MDR) and poor penetration into tumor tissues. The newly emerging nitric oxide (NO)-based gas therapy has been recognized to reduce MDR and has improved permeation into tumor tissue.