Open AccessNatural Nano-Drug Delivery System in Coptidis Rhizoma Extract with Modified Berberine Hydrochloride Pharmacokinetics
Author(s) -
Jing Zhao,
Qing Zhao,
Jingze Lu,
Dan Ye,
Sheng Mu,
Xiaodi Yang,
Weidong Zhang,
BingLiang Ma
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s323685
Subject(s) - zeta potential , berberine , chemistry , pharmacokinetics , pharmacology , cmax , biochemistry , nanoparticle , medicine , nanotechnology , materials science
This study aimed to evaluate the pharmaceutical and pharmacokinetic effects of the natural nanoparticles (Nnps) isolated from Coptidis Rhizoma extract on berberine hydrochloride (BBR) and systematically explore the related mechanisms.