Open AccessEvaluation of the Biological Activity of Folic Acid-Modified Paclitaxel-Loaded Gold Nanoparticles
Author(s) -
Bin Ren,
Zhong-Chao Cai,
XueJie Zhao,
Linsong Li,
MeiXia Zhao
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s322856
Subject(s) - hela , folate receptor , drug delivery , mtt assay , polyethylene glycol , chemistry , cancer cell , peg ratio , colloidal gold , biophysics , apoptosis , materials science , biochemistry , nanoparticle , cell , nanotechnology , biology , cancer , organic chemistry , genetics , finance , economics
Gold nanoparticles (AuNPs) with good physical and biological properties are often used in medicine, diagnostics, food, and similar industries. This paper explored an AuNPs drug delivery system that had good target selectivity for folate-receptor overexpressing cells to induce apoptosis.