Open AccessIntraosseous Injection of Calcium Phosphate Polymer-Induced Liquid Precursor Increases Bone Density and Improves Early Implant Osseointegration in Ovariectomized Rats
Author(s) -
Yanyan Zhou,
Zihe Hu,
Mingjie Ge,
Wenjing Jin,
Ruikang Tang,
Qi Li,
Weijian Xu,
Jianzhong Shi,
Zhijian Xie
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s321882
Subject(s) - osseointegration , ovariectomized rat , implant , osteoporosis , materials science , apatite , dentistry , bone tissue , calcium , tibia , biomedical engineering , chemistry , mineralogy , medicine , surgery , biochemistry , metallurgy , hormone
Osteoporosis, due to bone loss and structural deterioration, is a risk factor for dental implant failure, as it impedes initial stability and osseointegration. We aim to assess the effects of calcium phosphate polymer-induced liquid precursor (CaP-PILP) treatment, which significantly increases bone density and improves early implant osseointegration in ovariectomized rats.