Open AccessFunctionalized DMP-039 Hybrid Nanoparticle as a Novel mRNA Vector for Efficient Cancer Suicide Gene Therapy
Author(s) -
Gao Yan,
Ke Men,
Congbin Pan,
Jingmei Li,
Wu Jin,
Xiaohua Chen,
Sibei Lei,
Xiang Gao,
Xingmei Duan
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s319092
Subject(s) - suicide gene , vector (molecular biology) , genetic enhancement , nanoparticle , cancer , cancer therapy , gene , gene expression , messenger rna , cancer research , nanotechnology , computational biology , materials science , medicine , biology , genetics , recombinant dna
Gene therapy has emerged as a new strategy for cancer therapy. As an alternative nucleic acid material, messenger ribonucleic acid (mRNA) is being increasingly utilized in cancer gene therapy. However, unfulfilled requirements and a lack of ideal mRNA delivery vectors persist.