Open AccessIdentification of Novel Ligands for Targeted Antifibrotic Therapy of Chronic Pancreatitis
Author(s) -
Jessica Hung,
Rohni Awasthi,
Alexander L. Klibanov,
Kimberly A. Kelly
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s318331
Subject(s) - pancreatitis , identification (biology) , medicine , computational biology , biology , botany
Chronic pancreatitis (CP) is an inflammatory disorder of the pancreas that leads to impaired pancreatic function. The limited therapeutic options and the lack of molecular targeting ligands or non-serum-based biomarkers hinder the development of target-specific drugs. Thus, there is a need for an unbiased, comprehensive discovery and evaluation of pancreatitis-specific ligands.