Open AccessHollow CeO2 with ROS-Scavenging Activity to Alleviate Colitis in Mice
Author(s) -
Jing Yang,
Jinzhe Zhou,
Yingying Zhao,
Liangchen Zhu,
Guanghong Luo,
Bujun Ge
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s317261
Subject(s) - colitis , biocompatibility , proinflammatory cytokine , reactive oxygen species , nanomedicine , materials science , oxidative stress , pharmacology , inflammation , chemistry , immunology , nanotechnology , nanoparticle , medicine , biochemistry , metallurgy
Excessive production of reactive oxygen species (ROS) to induce high oxidative stress is one of the main causes of colitis; thus, it has been regarded as a therapeutic target for colitis treatment. And the nanomaterial-based therapeutic strategies are effective against colitis. However, the previous elaborately designed materials exhibit limited application due to the uncertain biocompatibility and complicated manufacturing processes.