Open AccessEnhanced Antibacterial and Anti-Biofilm Activities of Antimicrobial Peptides Modified Silver Nanoparticles
Author(s) -
Jian Xu,
Yuanpei Li,
Haojie Wang,
Mengxi Zhu,
Feng Wei,
Gaofeng Liang
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s315839
Subject(s) - nanocomposite , biofilm , biocompatibility , silver nanoparticle , dynamic light scattering , crystal violet , antimicrobial , nuclear chemistry , fourier transform infrared spectroscopy , materials science , chemistry , antibacterial activity , nanoparticle , microbiology and biotechnology , bacteria , chemical engineering , nanotechnology , organic chemistry , biology , engineering , genetics
The biofilms could protect bacteria from antibiotics and promote the production of drug-resistant strains, making the bacteria more difficult to be eradicated. Thus, we developed an AMP@PDA@AgNPs nanocomposite, which is formed by modifying silver nanoparticles (AgNPs) with antimicrobial peptides (AMP) modified nanocomposite to destroy biofilm in this study.