Open AccessAn Ultrasensitive Label-Free Fluorescent Aptasensor Platform for Detection of Sulfamethazine
Author(s) -
Yarong Wang,
Xiaoyu Yan,
Qiming Kou,
Qi Sun,
Yuexin Wang,
Ping Wu,
Lulan Yang,
Tang Jian,
Tao Le
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s307080
Subject(s) - detection limit , fluorescence , aptamer , chromatography , chemistry , rhodamine b , analyte , colloidal gold , förster resonance energy transfer , nanoparticle , materials science , nanotechnology , biochemistry , physics , quantum mechanics , photocatalysis , biology , genetics , catalysis
Sulfamethazine (SMZ) exposed in the environment can enter the human body through the food chain and pose a serious threat to human health. Therefore, it is important to develop a rapid and sensitive method for detecting SMZ in environmental samples. In order to fastly and quantitatively detect SMZ in environmental samples, we developed a label-free fluorescent aptasensor based on specific aptamer (SMZ1S) and fluorescence resonance energy transfer (FRET) between gold nanoparticles (AuNPs) and rhodamine B (RhoB).