Open AccessIn vitro Anticancer Effects of Vernonia amygdalina Leaf Extract and Green-Synthesised Silver Nanoparticles
Author(s) -
Julia Joseph,
Kang Zi Khor,
Emmanuel Jairaj Moses,
Vuanghao Lim,
Mohd Yusmaidie Aziz,
Nozlena Abdul Samad
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s303921
Subject(s) - vernonia amygdalina , silver nanoparticle , apoptosis , cytotoxicity , dna fragmentation , nanoparticle , ethanol , in vitro , nuclear chemistry , viability assay , chemistry , traditional medicine , mcf 7 , cell cycle , mtt assay , materials science , biochemistry , cancer cell , nanotechnology , medicine , cancer , programmed cell death , human breast
Vernonia amygdalina (VA) is a traditional African herbal medicine that has been reported to possess anticancer properties. However, the anticancer properties of VA silver nanoparticles have not been studied. The aim of the study was to examine and evaluate the anticancer activities of VA leaf extracts and VA silver nanoparticles on the human breast cancer cell line, MCF-7.