Open AccessRole of Oxidative Stress in La2O3 Nanoparticle-Induced Cytotoxicity and Apoptosis in CHANG and HuH-7 Cells
Author(s) -
Hanouf Almukhlafi,
Daoud Ali,
Bader O. Almutairi,
Khadijah N. Yaseen,
Nouf M. Alyami,
Rafa Almeer,
Saad Alkahtani,
Saud Alarifi
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s302478
Subject(s) - cytotoxicity , oxidative stress , reactive oxygen species , lactate dehydrogenase , superoxide dismutase , comet assay , microbiology and biotechnology , biophysics , apoptosis , dna damage , glutathione , nanotoxicology , chemistry , dichlorofluorescein , biochemistry , toxicity , biology , dna , enzyme , in vitro , organic chemistry
Nanoparticles are extensively applied in pharmaceutical, agriculture, food processing industries, and in many other fields. In the current experiment, we have determined the mechanism of toxicity of lanthanum oxide nanoparticles (La 2 O 3 NPs) on human liver cell lines.