Open Access
Nanoparticles of Chitosan/Poly(D,L-Lactide-Co-Glycolide) Enhanced the Immune Responses of Haemonchus contortus HCA59 Antigen in Model Mice
Author(s) -
Qiangqiang Wang,
Xin Sun,
Xin Huang,
JinShun Huang,
Muhammad Waqqas Hasan,
Yan Ren,
Xiangrui Li,
Xiaoling Song
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s301851
Subject(s) - plga , immune system , antigen , adjuvant , cd8 , chitosan , biology , microbiology and biotechnology , immunology , chemistry , in vitro , biochemistry
Hepatocellular carcinoma-associated antigen 59 (HCA59) from excretory/secretory products of Haemonchus contortus is known to have the ability to modulate the functions of host cells. However, its immunogenicities using different nanoparticles adjuvants remain poorly understood.