Open AccessPerformance of Nano-Hydroxyapatite/Beta-Tricalcium Phosphate and Xenogenic Hydroxyapatite on Bone Regeneration in Rat Calvarial Defects: Histomorphometric, Immunohistochemical and Ultrastructural Analysis
Author(s) -
Igor da Silva Brum,
Lúcio Frigo,
P. Santos,
Carlos Nelson Elias,
Guilherme Aparecido Monteiro Duque da Fonseca,
Jorge José de Carvalho
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s301470
Subject(s) - biomaterial , in vivo , chemistry , matrix (chemical analysis) , biomedical engineering , extracellular matrix , regeneration (biology) , implant , materials science , microbiology and biotechnology , biochemistry , medicine , biology , surgery , chromatography
Synthetic biomaterials have played an increasingly prominent role in the substitution of naturally derived biomaterials in current surgery practice. In vitro and in vivo characterization studies of new synthetic biomaterials are essential to analyze their physicochemical properties and the underlying mechanisms associated with the modulation of the inflammatory process and bone healing.