Open AccessWound Healing Activity of Opuntia ficus-indica Fixed Oil Formulated in a Self-Nanoemulsifying Formulation
Author(s) -
Abdulrahman E. Koshak,
Mardi M. Algandaby,
Mohammad Ibrahim Mujallid,
Ashraf B. Abdel-Naim,
Nabil A. Alhakamy,
Usama A. Fahmy,
Anas Alfarsi,
Shaimaa M. Badr-Eldin,
Thikryat Neamatallah,
Mohammed Z. Nasrullah,
Hossam M. Abdallah,
Ahmed Esmat
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s299696
Subject(s) - wound healing , hydroxyproline , angiogenesis , vascular endothelial growth factor , in vivo , biomedical engineering , chemistry , pharmacology , traditional medicine , medicine , biology , surgery , vegf receptors , biochemistry , microbiology and biotechnology
Delayed wound healing represents a common health hazard. Traditional herbal products have been often utilized to promote wound contraction. The current study aimed at assessing the wound healing activity of Opuntia ficus-indica seed oil (OFI) and its self-nanoemulsifying drug delivery system (OFI-SNEDDS) formula in a rat model of full-thickness skin excision.