Open AccessEngineering Exosome-Like Nanovesicles Derived from Asparagus cochinchinensis Can Inhibit the Proliferation of Hepatocellular Carcinoma Cells with Better Safety Profile
Author(s) -
Lei Zhang,
Feng-Jun He,
Lina Gao,
Minghui Cong,
Juan Sun,
Jialu Xu,
Yutong Wang,
Yang Hu,
Sajid Asghar,
Lihong Hu,
Hongzhi Qiao
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s293067
Subject(s) - endocytosis , exosome , in vivo , apoptosis , cytotoxicity , chemistry , pharmacology , microbiology and biotechnology , microvesicles , biology , in vitro , biochemistry , cell , microrna , gene
Exosomes are a type of membrane vesicles secreted by living cells. Recent studies suggest exosome-like nanovesicles (ELNVs) from fruits and vegetables are involved in tissue renewal process and functional regulation against inflammatory diseases or cancers. However, there are few reports on ELNVs derived from medicinal plants.