Open AccessNanosonosensitizer-Augmented Sonodynamic Therapy Combined with Checkpoint Blockade for Cancer Immunotherapy
Author(s) -
Xiaoning Lin,
Rong Huang,
Yanlin Huang,
Kai Wang,
Heng Li,
Yiheng Bao,
Chaohui Wu,
Yi Zhang,
Xin-Hua Tian,
Xiaomin Wang
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s290796
Subject(s) - sonodynamic therapy , immunotherapy , cancer research , adjuvant , medicine , immune system , cancer immunotherapy , immune checkpoint , in vivo , combination therapy , pretargeting , cancer , blockade , pharmacology , immunology , antibody , monoclonal antibody , biology , pathology , alternative medicine , receptor , microbiology and biotechnology , radioimmunotherapy
Sonodynamic therapy (SDT) has good targeting and non-invasive advantages in the treatment of solid cancers, and checkpoint blockade immunotherapy is also a promising treatment to cure cancer. However, their antitumor effects are not sufficient due to some inherent factors. Some studies that combined SDT with immunotherapy or nanoparticles have managed to enhance its efficiency to treat cancers.