Open AccessNanostructured Cellulose–Gellan–Xyloglucan–Lysozyme Dressing Seeded with Mesenchymal Stem Cells for Deep Second-Degree Burn Treatment
Author(s) -
Carolina Maria Costa de Oliveira Souza,
Camilla Mariane Menezes Souza,
Bassam Felipe Mogharbel,
Ana Carolina Irioda,
Célia Regina Cavichiolo Franco,
Maria Rita Sierakowski,
Katherine Athayde Teixeira de Carvalho
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s289868
Subject(s) - xyloglucan , mesenchymal stem cell , lysozyme , in vivo , bacterial cellulose , gellan gum , membrane , materials science , immunocytochemistry , cellulose , confocal microscopy , adhesion , biophysics , biomedical engineering , chemistry , biochemistry , microbiology and biotechnology , biology , pathology , medicine , food science , composite material
In deep burns, wound contraction and hypertrophic scar formation can generate functional derangement and debilitation of the affected part. In order to improve the quality of healing in deep second-degree burns, we developed a new treatment in a preclinical model using nanostructured membranes seeded with mesenchymal stem cells (MSCs).