Open AccesstLyP-1 Peptide Functionalized Human H Chain Ferritin for Targeted Delivery of Paclitaxel
Author(s) -
Yuanmeng Ma,
Ruike Li,
Yixin Dong,
Chaoqun You,
Shenlin Huang,
Xun Li,
Fei Wang,
Yu Zhang
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s289005
Subject(s) - paclitaxel , cytotoxicity , in vivo , flow cytometry , mtt assay , confocal microscopy , cancer cell , in vitro , cancer research , cell penetrating peptide , nude mouse , ferritin , chemistry , cell , microbiology and biotechnology , biology , cancer , biochemistry , genetics
The aims of this study were to test the feasibility, targeting specificity and anticancer therapeutic efficacy of CendR motif tLyP-1 functionalized at the N-terminal of ferritin for paclitaxel (PTX) delivery.