Open AccessAu-Pt Nanoparticle Formulation as a Radiosensitizer for Radiotherapy with Dual Effects
Author(s) -
Song Yang,
Gaohua Han,
Quan Chen,
Lei Yu,
Peng Wang,
Qi Zhang,
Jiancheng Dong,
Wei Zhang,
Junxing Huang
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s287523
Subject(s) - radiosensitizer , radiosensitivity , materials science , radiation therapy , mtt assay , nanoparticle , polyethylene glycol , dynamic light scattering , in vitro , chemistry , radiochemistry , biophysics , nuclear chemistry , nanotechnology , medicine , biochemistry , biology
Radiotherapy occupies an essential position as one of the most significant approaches for the clinical treatment of cancer. However, we cannot overcome the shortcoming of X-rays which is the high value of the oxygen enhancement ratio (OER). Radiosensitizers with the ability to enhance the radiosensitivity of tumor cells provide an alternative to changing X-rays to protons and heavy ion radiotherapy.