Open AccessGraphene Oxide Theranostic Effect: Conjugation of Photothermal and Photodynamic Therapies Based on an in vivo Demonstration
Author(s) -
María Paulina Romero,
Hilde Harb Buzzá,
Mirian Denise Stringasci,
Bianca Martins Estevão,
Cecilia C C Silva,
Marcelo A. Pereira-da-Silva,
Natália Mayumi Inada,
Vanderlei Salvador Bagnato
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s287415
Subject(s) - photothermal therapy , in vivo , photodynamic therapy , indocyanine green , context (archaeology) , materials science , nanomedicine , nanotechnology , biocompatibility , rhodamine b , cancer research , medicine , chemistry , nanoparticle , photocatalysis , pathology , biochemistry , microbiology and biotechnology , organic chemistry , biology , paleontology , metallurgy , catalysis
Cancer is the second leading cause of death globally and is responsible, where about 1 in 6 deaths in the world. Therefore, there is a need to develop effective antitumor agents that are targeted only to the specific site of the tumor to improve the efficiency of cancer diagnosis and treatment and, consequently, limit the unwanted systemic side effects currently obtained by the use of chemotherapeutic agents. In this context, due to its unique physical and chemical properties of graphene oxide (GO), it has attracted interest in biomedicine for cancer therapy.