Open Access<p>Graphene Oxide/Copper Nanoderivatives-Modified Chitosan/Hyaluronic Acid Dressings for Facilitating Wound Healing in Infected Full-Thickness Skin Defects</p>
Author(s) -
Ying Yang,
Zhonggen Dong,
Min Li,
Lihong Liu,
Hang Luo,
Pu Wang,
Xinghua Yang,
Kechao Zhou,
Shaorong Lei
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s278631
Subject(s) - hyaluronic acid , chitosan , wound healing , in vivo , granulation tissue , biocompatibility , antimicrobial , in vitro , materials science , pharmacology , medicine , chemistry , microbiology and biotechnology , surgery , biochemistry , biology , metallurgy , anatomy
Wound healing, especially of infected wounds, remains a clinical challenge in plastic surgery. This study aimed to manufacture a novel and multifunctional wound dressing by combining graphene oxide/copper nanocomposites (GO/Cu) with chitosan/hyaluronic acid, providing significant opportunities for the therapy of wound repair in wounds with a high risk of bacterial infection.