Open Access<p>Cationic Solid Lipid Nanoparticles of Resveratrol for Hepatocellular Carcinoma Treatment: Systematic Optimization, in vitro Characterization and Preclinical Investigation</p>
Author(s) -
Mahfoozur Rahman,
Waleed Hassan Almalki,
Obaid Afzal,
Abdulmalik Saleh Alfawaz Altamimi,
Imran Kazmi,
Fahad A. Al-Abbasi,
Hani Choudhry,
Sattam Khulaif Alenezi,
Md. Abul Barkat,
Sarwar Beg,
Vikas Kumar,
Abdulsalam Alhalmi
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s277545
Subject(s) - in vivo , solid lipid nanoparticle , pharmacology , resveratrol , cytotoxicity , biodistribution , in vitro , sorafenib , hepatocellular carcinoma , chemistry , drug , cancer research , medicine , biochemistry , biology , microbiology and biotechnology
The present study focuses on the development and evaluation of the resveratrol (RV)-loaded cationic solid lipid nanoparticles (RV-c-SLNs) for the management of hepatocellular carcinoma (HCC).