Open Access<p>Host Immune Response Triggered by Graphene Quantum-Dot-Mediated Photodynamic Therapy for Oral Squamous Cell Carcinoma</p>
Author(s) -
Xiliu Zhang,
Hongyu Li,
Yi Chen,
Guosheng Chen,
Ye Li,
Ying Zhou,
Guanhui Chen,
Yiming Li,
Yi He,
Dongsheng Yu
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s276153
Subject(s) - photodynamic therapy , phototoxicity , in vivo , photosensitizer , cancer research , materials science , immune system , cytotoxic t cell , chemistry , biocompatibility , in vitro , immunology , medicine , biology , biochemistry , photochemistry , metallurgy , microbiology and biotechnology , organic chemistry
With the innovation of photosensitizers, photodynamic therapy is now widely used in antitumor detection and treatment. Graphene quantum dots (GQDs) are proposed as a promising alternative photosensitizer due to their high biocompatibility, specific photoactivity, and strong tumor concentration. However, the changes in host immunity triggered by GQDs have only rarely been reported.