Open Access<p>Oral Exposure to ZnO Nanoparticles Disrupt the Structure of Bone in Young Rats via the OPG/RANK/RANKL/IGF-1 Pathway</p>
Author(s) -
Xinyue Xu,
Yu Tang,
Yuanyuan Lang,
Yanling Liu,
Wenshu Cheng,
Hengyi Xu,
Yang Liu
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s275553
Subject(s) - osteoprotegerin , endocrinology , medicine , alkaline phosphatase , rankl , chemistry , osteoporosis , bone mineral , insulin like growth factor , zinc , receptor , growth factor , biochemistry , enzyme , organic chemistry , activator (genetics)
To evaluate the effects of ZnO NPs on bone growth in rats and explore the possible mechanisms of action.