Open Access<p>Nanoscale Thermosensitive Hydrogel Scaffolds Promote the Chondrogenic Differentiation of Dental Pulp Stem and Progenitor Cells: A Minimally Invasive Approach for Cartilage Regeneration</p>
Author(s) -
Wael Talaat,
Smriti Aryal Ac,
Sausan Al Kawas,
A. B. Rani Samsudin,
Nadia G. Kandile,
David Harding,
Mohamed M. Ghoneim,
Waleed Zeiada,
Jayalakshmi Jagal,
Ahmed Aboelnaga,
Mohamed Haider
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s274418
Subject(s) - chondrogenesis , self healing hydrogels , biomedical engineering , mesenchymal stem cell , dental pulp stem cells , nanocellulose , materials science , scaffold , regeneration (biology) , cartilage , biocompatibility , in vivo , progenitor cell , stem cell , chemistry , microbiology and biotechnology , anatomy , cellulose , medicine , organic chemistry , polymer chemistry , metallurgy , biology
Several scaffolds and cell sources are being investigated for cartilage regeneration. The aim of the study was to prepare nanocellulose-based thermosensitive injectable hydrogel scaffolds and assess their potential as 3D scaffolds allowing the chondrogenic differentiation of embedded human dental pulp stem and progenitor cells (hDPSCs).