Open AccessDevelopment and Optimization of Terpene-Enriched Vesicles (Terpesomes) for Effective Ocular Delivery of Fenticonazole Nitrate: In vitro Characterization and in vivo Assessment
Author(s) -
Rofida Albash,
Abdulaziz Mohsen Al-mahallawi,
Mariam Hassan,
Ahmed Adel Alaa-Eldin
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s274290
Subject(s) - in vivo , in vitro , vesicle , terpene , chemistry , biochemistry , biology , microbiology and biotechnology , membrane
The aim of the current study was to load fenticonazole nitrate, a slightly water-soluble antifungal agent, into terpene-enriched phospholipid vesicles (terpesomes) as a potential delivery system for the management of ocular fungal infection.