Open Access<p>Combating Intracellular Pathogens with Nanohybrid-Facilitated Antibiotic Delivery</p>
Author(s) -
Rajendran J.C. Bose,
Nagendran Tharmalingam,
Yonghyun Choi,
Thiagarajan Madheswaran,
Ramasamy Paulmurugan,
Jason R. McCarthy,
Soo−Hong Lee,
Hansoo Park
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s271850
Subject(s) - intracellular , doxycycline , antibiotics , cationic polymerization , drug delivery , biophysics , surface charge , vancomycin , drug carrier , chemistry , staphylococcus aureus , minimum inhibitory concentration , microbiology and biotechnology , materials science , bacteria , biochemistry , biology , organic chemistry , genetics
Lipid polymer hybrid nanoparticles (LPHNPs) have been widely investigated in drug and gene delivery as well as in medical imaging. A knowledge of lipid-based surface engineering and its effects on how the physicochemical properties of LPHNPs affect the cell-nanoparticle interactions, and consequently how it influences the cytological response, is in high demand.