Open Access<p>In vivo Monitoring and Assessment of Exogenous Mesenchymal Stem Cell-Derived Exosomes in Mice with Ischemic Stroke by Molecular Imaging</p>
Author(s) -
Rong Xu,
Yingying Bai,
Shudan Min,
Xiaoxuan Xu,
Tianyu Tang,
Shenghong Ju
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s271519
Subject(s) - mesenchymal stem cell , neurogenesis , angiogenesis , stroke (engine) , medicine , in vivo , fractional anisotropy , diffusion mri , microvesicles , brain ischemia , pathology , white matter , magnetic resonance imaging , ischemia , ischemic stroke , cancer research , microbiology and biotechnology , microrna , biology , radiology , mechanical engineering , biochemistry , gene , engineering
Mesenchymal stem cell-derived exosomes (MSC-exos) are considered an important restorative treatment for ischemic stroke. However, the migration ability and survival of exogenous MSC-exos remain unclear. Here, we investigated whether MSC-exos migrate into the ischemic brain and play a protective role against ischemic stroke.