Open Access<p>Enhanced Osseointegration of Titanium Implants by Surface Modification with Silicon-doped Titania Nanotubes</p>
Author(s) -
Xixi Zhao,
Linna You,
Tao Wang,
Xianjun Zhang,
Zexi Li,
Luguang Ding,
Jiaying Li,
Xiao Chu,
Fengxuan Han,
Bin Li
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s270311
Subject(s) - osseointegration , materials science , titanium , surface modification , anodizing , nanotechnology , nanotube , biomedical engineering , implant , carbon nanotube , chemical engineering , composite material , metallurgy , medicine , surgery , aluminium , engineering
Despite great progress made in developing orthopedic implants, the development of titanium (Ti) implants with ideal early osseointegration remains a big challenge. Our pilot study has demonstrated that Si-TiO 2 nanotubes on the surface of Ti substrates could enhance their osteogenic activity. Hence, in this study, we aim to comprehensively evaluate the effects of silicon-doped titania (Si-TiO 2 ) nanotubes on the osseointegration property of Ti implants.