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Vertical bone augmentation without osseous walls to support the stability of clots and bone grafts remains a challenge in dental implantology. The objectives of this study were to confirm that cortical perforation of the recipient bed is necessary and to evaluate whether nanohydroxyapatite (nHA) block grafts coated with recombinant human vascular endothelial growth factor 165 (rhVEGF 165 ) and cortical perforation can improve vertical bone regeneration.

international journal of nanomedicine

&lt;p&gt;Vertical Guided Bone Regeneration in the Rabbit Calvarium Using Porous Nanohydroxyapatite Block Grafts Coated with rhVEGF&lt;sub&gt;165&lt;/sub&gt; and Cortical Perforation&lt;/p&gt;