Open AccessCancer Cell–Membrane Biomimetic Boron Nitride Nanospheres for Targeted Cancer Therapy
Author(s) -
Shini Feng,
Yajing Ren,
Hui Li,
Yunfei Tang,
Jinyu Yan,
Zeyuan Shen,
Huijie Zhang,
Fuxue Chen
Publication year - 2021
Publication title -
international journal of nanomedicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s266948
Subject(s) - hela , drug delivery , cancer cell , doxorubicin , targeted drug delivery , cancer research , cytotoxicity , cell , materials science , pharmacology , cancer , chemistry , nanotechnology , chemotherapy , medicine , biochemistry , in vitro , surgery
Nanomaterial-based drug-delivery systems allowing for effective targeted delivery of smallmolecule chemodrugs to tumors have revolutionized cancer therapy. Recently, as novel nanomaterials with outstanding physicochemical properties, boron nitride nanospheres (BNs) have emerged as a promising candidate for drug delivery. However, poor dispersity and lack of tumor targeting severely limit further applications. In this study, cancer cell-membrane biomimetic BNs were designed for targeted anticancer drug delivery.