Open Access<p>Silica Nanoparticles Disturb Ion Channels and Transmembrane Potentials of Cardiomyocytes and Induce Lethal Arrhythmias in Mice</p>
Author(s) -
Yaqin Liu,
Si-Meng Xue,
Peng Zhang,
Li Xu,
Deping Wang,
Guang Li,
JiMin Cao
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s261692
Subject(s) - in vivo , in vitro , biophysics , membrane potential , myocyte , ion channel , patch clamp , endocytosis , pharmacology , calcium , toxicity , chemistry , electrophysiology , microbiology and biotechnology , medicine , biology , biochemistry , cell , receptor
The toxicity of silica nanoparticles (SiNPs) on cardiac electrophysiology has seldom been evaluated.