Open Access<p>Transferrin Receptor-Targeted PEG-PLA Polymeric Micelles for Chemotherapy Against Glioblastoma Multiforme</p>
Author(s) -
Sun Park,
Yue Xiao,
Qianqian Di,
Wenjing Ma,
Ranjeny Thomas,
Qingqing Wang,
Weilin Chen
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s257459
Subject(s) - glioma , paclitaxel , transferrin receptor , cancer research , blood–brain barrier , chemotherapy , drug delivery , micelle , pharmacology , in vitro , targeted drug delivery , chemistry , transferrin , medicine , drug , biochemistry , central nervous system , organic chemistry , aqueous solution
The safe and efficient delivery of chemotherapeutic agents is critical to glioma therapy. However, chemotherapy for glioma is extremely challenging because the blood-brain barrier (BBB) rigorously prevents drugs from reaching the tumor region.