Open Access<p>Delivery of MSCs with a Hybrid β-Sheet Peptide Hydrogel Consisting IGF-1C Domain and D-Form Peptide for Acute Kidney Injury Therapy</p>
Author(s) -
Hongfeng Wang,
Yuna Shang,
Xiaoniao Chen,
Zhongyan Wang,
Dashuai Zhu,
Yue Liu,
Chuyue Zhang,
Pu Chen,
Jie Wu,
Lingling Wu,
Deling Kong,
Zhimou Yang,
Zongjin Li,
Xiangmei Chen
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s254635
Subject(s) - self healing hydrogels , mesenchymal stem cell , tissue engineering , stem cell , stem cell therapy , angiogenesis , regenerative medicine , regeneration (biology) , peptide , microbiology and biotechnology , materials science , chemistry , biophysics , cancer research , biomedical engineering , medicine , biochemistry , biology , polymer chemistry
By providing a stem cell microenvironment with particular bioactive constituents in vivo, synthetic biomaterials have been progressively successful in stem cell-based tissue regeneration by enhancing the engraftment and survival of transplanted cells. Designs with bioactive motifs to influence cell behavior and with D-form amino acids to modulate scaffold stability may be critical for the development and optimization of self-assembling biomimetic hydrogel scaffolds for stem cell therapy.