Open Access<p>Synergistic Effects of Physicochemical Parameters on Bio-Fabrication of Mint Silver Nanoparticles: Structural Evaluation and Action Against HCT116 Colon Cancer Cells</p>
Author(s) -
Bilal Javed,
ZiaurRehman Mashwani
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s254402
Subject(s) - silver nanoparticle , nuclear chemistry , surface plasmon resonance , annexin , chemistry , nanoparticle , cytotoxicity , materials science , nanotechnology , chemical engineering , apoptosis , biochemistry , in vitro , engineering
Physicochemical parameters such as temperature, pH, the concentration of the AgNO 3 and ratio of reactants act synergistically to influence the reaction kinetics, molecular mechanics, enzymatic catalysis and protein conformations that aid to affect the size, shape and biochemical corona of nanoparticles. The present study was performed to investigate the influence of reaction parameters on the bio-fabrication of silver nanoparticles (AgNPs) by using Mentha arvensis and to determine their potential to control the proliferation of colon cancer cells'.