Open Access<p>Ultrasound Combined with Core Cross-Linked Nanosystem for Enhancing Penetration of Doxorubicin Prodrug/Beta-Lapachone into Tumors</p>
Author(s) -
Qianyan Li,
Wei Hou,
Meixuan Li,
Hemin Ye,
Huanan Li,
Zhibiao Wang
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s251277
Subject(s) - prodrug , doxorubicin , in vivo , penetration (warfare) , drug delivery , chemistry , cancer research , materials science , biophysics , nanotechnology , medicine , chemotherapy , biochemistry , biology , surgery , microbiology and biotechnology , operations research , engineering
Nanosized drug delivery systems (NDDSs) have shown excellent prospects in tumor therapy. However, insufficient penetration of NDDSs has significantly impeded their development due to physiological instability and low passive penetration efficiency.