Open Access<p>Development and Characterization of A New Dimethicone Nanoemulsion and its Application for Electronic Gastroscopy Examination</p>
Author(s) -
SiShen Feng,
Ying Zhao,
Qing Yi Xu,
Huimin Li,
Yuxiu Huang,
HuanHuan Liu,
CangBao Xu
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s251113
Subject(s) - dispersity , viscosity , solubility , materials science , chromatography , defoamer , phase (matter) , particle size , chemistry , organic chemistry , dispersant , polymer chemistry , composite material , dispersion (optics) , physics , optics
Although the effective and safe medical defoamers, dimethicone (DM) and simethicone (SM) are widely used in electronic gastroscope examination (EGE), their preparations are presented in the form of suspensions or emulsions, these are untransparent or milk-like in appearance and can easily cause misdiagnosis as a result of an unclear field of vision if the doctor does not master the amount of defoamer or operates incorrectly. At the same time, it is also difficult to wash out the camera and pipeline, due to the large oil droplets of preparations. The purpose of this study was to develop a new clear and transparent oil in water (O/W) DM nanoemulsions (DMNs) and observe the effect of application in EGE.