Open Access<p>Response Surface Methodology for Statistical Optimization of Chitosan/Alginate Nanoparticles as a Vehicle for Recombinant Human Bone Morphogenetic Protein-2 Delivery</p>
Author(s) -
Maryam Zohri,
Hamid Akbari Javar,
Taraneh Gazori,
Mohammad Reza Khoshayand,
Seyed Hamid AghaeeBakhtiari,
Mohammad Hossein Ghahremani
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s250630
Subject(s) - response surface methodology , box–behnken design , dispersity , chitosan , particle size , materials science , nanoparticle , human bone , bone morphogenetic protein 2 , chemical engineering , nuclear chemistry , chromatography , nanotechnology , chemistry , in vitro , biochemistry , polymer chemistry , engineering
In this study, chitosan/alginate nanoparticles are prospected as a carrier for controlled release of recombinant human bone morphogenetic protein-2 (rhBMP-2).