Open Access<p>Novel pH-Sensitive Urushiol-Loaded Polymeric Micelles for Enhanced Anticancer Activity</p>
Author(s) -
Hao Zhou,
Zhiwen Qi,
Xingying Xue,
Chengzhang Wang
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s250564
Subject(s) - micelle , ethylene glycol , in vivo , amphiphile , bioavailability , chemistry , cytotoxicity , critical micelle concentration , copolymer , in vitro , particle size , nuclear chemistry , chromatography , biophysics , polymer , organic chemistry , biochemistry , pharmacology , aqueous solution , medicine , microbiology and biotechnology , biology
The aim of this study was to develop a means of improving the bioavailability and anticancer activity of urushiol by developing an urushiol-loaded novel tumor-targeted micelle delivery system based on amphiphilic block copolymer poly(ethylene glycol)-b-poly-(β-amino ester) (mPEG-PBAE).