Open Access<p>Bioinspired Nanofiber Scaffold for Differentiating Bone Marrow-Derived Neural Stem Cells to Oligodendrocyte-Like Cells: Design, Fabrication, and Characterization</p>
Author(s) -
Fatemeh Rasti Boroojeni,
Shohreh Mashayekhan,
Hojjat-Allah Abbaszadeh,
Mohamadhasan Ansarizadeh,
Maryam-Sadat Khoramgah,
Vafa Rahimi-Movaghar
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s248509
Subject(s) - nanofiber , scaffold , materials science , neural stem cell , chitosan , neural tissue engineering , gelatin , oligodendrocyte , mesenchymal stem cell , polycaprolactone , biomedical engineering , stem cell , biophysics , nanotechnology , microbiology and biotechnology , chemistry , myelin , biology , medicine , biochemistry , neuroscience , central nervous system , polymer , composite material
Researchers are trying to study the mechanism of neural stem cells (NSCs) differentiation to oligodendrocyte-like cells (OLCs) as well as to enhance the selective differentiation of NSCs to oligodendrocytes. However, the limitation in nerve tissue accessibility to isolate the NSCs as well as their differentiation toward oligodendrocytes is still challenging.