Open Access<p>Liposomal Encapsulated Curcumin Effectively Attenuates Neuroinflammatory and Reactive Astrogliosis Reactions in Glia Cells and Organotypic Brain Slices</p>
Author(s) -
Christina Schmitt,
Anna Lechanteur,
François Cossais,
Coralie Bellefroid,
Philipp Arnold,
Ralph Lucius,
Janka HeldFeindt,
Géraldine Piel,
Kirsten Hattermann
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s245300
Subject(s) - curcumin , astrogliosis , neuroinflammation , microglia , pharmacology , glial scar , medicine , astrocyte , neuroprotection , chemistry , inflammation , central nervous system , immunology
The polyphenolic spice and food coloring ingredient curcumin has beneficial effects in a broad variety of inflammatory diseases. Amongst them, curcumin has been shown to attenuate microglia reaction and prevent from glial scar formation in spinal cord and brain injuries.