Open Access<p>Characterization and Dissolution Study of Micellar Curcumin-Spray Dried Powder for Oral Delivery</p>
Author(s) -
Nina Wijiani,
Dewi Isadiartuti,
M. Agus Syamsur Rijal,
Helmy Yusuf
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s245050
Subject(s) - curcumin , dissolution , amorphous solid , bioavailability , solubility , spray drying , dissolution testing , aqueous solution , materials science , nuclear chemistry , micelle , chromatography , high performance liquid chromatography , differential thermal analysis , thermal analysis , sucrose , chemistry , organic chemistry , biochemistry , pharmacology , diffraction , biopharmaceutics classification system , medicine , physics , optics , thermal , meteorology
Curcumin faces a major challenge in clinical use due to its poor aqueous solubility, which affects its bioavailability over oral use. The present study was carried out to overcome this problem.