Open Access<p>Induction of Robust Immune Responses by CpG-ODN-Loaded Hollow Polymeric Nanoparticles for Antiviral and Vaccine Applications in Chickens</p>
Author(s) -
Shu Lin,
Bing Yao,
Che Ming Jack Hu,
Hui-Wen Chen
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s241492
Subject(s) - adjuvant , cpg oligodeoxynucleotide , immune system , immunopotentiator , cpg site , cd80 , biology , immunology , virology , cd40 , cytotoxic t cell , in vitro , gene expression , biochemistry , gene , dna methylation
Poultry vaccine has limited choices of adjuvants and is facing severe threat of infectious diseases due to ineffective of widely used commercial vaccines. Thus, development of novel adjuvant that offers safe and effective immunity is of urgent need.