Open Access<p>Novel <em>N</em>-(Substituted) Thioacetamide Quinazolinone Benzenesulfonamides as Antimicrobial Agents</p>
Author(s) -
Mostafa M. Ghorab,
Ali S. Alqahtani,
Aiten M. Soliman,
Ahmed Askar
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s241433
Subject(s) - antimicrobial , dna gyrase , staphylococcus aureus , minimum inhibitory concentration , nuclear chemistry , bacteria , microbiology and biotechnology , chemistry , biology , escherichia coli , biochemistry , genetics , gene
With the rapid emergence of antibiotic resistance, efforts are being made to obtain new selective antimicrobial agents. Hybridization between quinazolinone and benzenesulfonamide can provide new antimicrobial candidates. Also, the use of nanoparticles can help boost drug efficacy and lower side effects.