Open Access<p>Multifunctional Superparamagnetic Iron Oxide Nanoparticles Conjugated with Aβ Oligomer-Specific scFv Antibody and Class A Scavenger Receptor Activator Show Early Diagnostic Potentials for Alzheimer’s Disease</p>
Author(s) -
Xiaoge Liu,
Lun Zhang,
Shuai Lü,
Dongqun Liu,
Lingxiao Zhang,
Xiaolin Yu
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s240953
Subject(s) - flow cytometry , chemistry , microglia , scavenger receptor , in vivo , cancer research , biophysics , pathology , microbiology and biotechnology , immunology , medicine , biology , inflammation , biochemistry , lipoprotein , cholesterol
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. Diagnosing AD before symptoms arise will facilitate earlier intervention. The early diagnostic approaches are thus urgently needed.