Open Access<p>Directional Osteo-Differentiation Effect of hADSCs on Nanotopographical Self-Assembled Polystyrene Nanopit Surfaces</p>
Author(s) -
Changhong Zhao,
Xuebin Song,
Xiaoyuan Lü
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s240300
Subject(s) - nanotopography , extracellular matrix , materials science , cell adhesion , tissue engineering , nanotechnology , stem cell , adhesion , cell , microbiology and biotechnology , biomedical engineering , biophysics , chemistry , biology , medicine , biochemistry , composite material
Cells exhibit high sensitivity and a diverse response to the nanotopography of the extracellular matrix, thereby endowing materials with instructive performances formerly reserved for growth factors. This finding leads to opportunities for improvement. However, the interplay between the topographical surface and cell behaviors remains incompletely understood.