Open Access<p>Exosomes as Actively Targeted Nanocarriers for Cancer Therapy</p>
Author(s) -
Yan Wang,
Yingru Zhang,
Gang Cai,
Qi Li
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s239548
Subject(s) - nanocarriers , microvesicles , drug , cancer research , pharmacology , cancer , exosome , medicine , drug delivery , microrna , chemistry , nanotechnology , materials science , biochemistry , gene
In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism's own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes.